Clinical trial of sustained-release artificial tears in keratoconjunctivitis sicca and Sjögren's syndrome

Keratoconjunctivitis sicca due to sarcoidosis.

SARCOIDOSIS is well recognized as a cause of swelling of the lacrimal glands and enters into the differential diagnosis of tumours of this region (DukeElder, 1952). Such swellings may be followed, in some cases, by a form of keratoconjunctivitis sicca (Ainslie and James, 1956; Gruber, 1956). The association of systemic sarcoidosis with keratoconjunctivitis sicca in the absence of swelling of th...

Iatrogenic keratoconjunctivitis sicca in a dog

Qualitative and quantitative abnormalities in primary components of the tear can alter the dynamics of the lacrimal film, compromising its function. Lipids, an aqueous fraction and mucoproteins constitute the lacrimal film. Keratoconjunctivitis sicca (KCS) is a disease commonly diagnosed in dogs. It is characterized by the deficiency of the aqueous fraction in the lacrimal film that results in ...

A New Conception of Keratoconjunctivitis Sicca

The role of inflammation and antiinflammation therapies in keratoconjunctivitis sicca

PURPOSE To review and integrate recent advances in identifying the role of inflammation in the pathogenesis of dry eye conditions and the biological rationale and practical clinical aspects of newer, antiinflammatory theories. METHODS A comprehensive literature survey. RESULTS AND CONCLUSION Keratoconjunctivitis Sicca (KCS) is a multifactorial and complex disorder in which ocular surface in...

Long-term course of tear gland function in patients with keratoconjunctivitis sicca and Sjögren's syndrome.

AIMS To assess the course of tear gland function of patients with keratoconjunctivitis sicca (KCS) associated with primary (KCS-PSS) or secondary Sjögren's syndrome (KCS-SSS), and of patients with KCS not related to Sjögren's syndrome (KCS-NS). METHODS In 106 patients with dry eye an ophthalmic diagnosis of KCS was made. Subsequent evaluations revealed a diagnosis of KCS-PSS in 31, KCS-SS in ...